Nanotechnology and COVID-19: Potential application for treatment
Nanotechnology and COVID-19: Potential application for treatment
sona talaei,1,*hasan mellatyar,2
1. Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran 2. Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Introduction: The novel coronavirus (2019-nCoV) emerged in China at the end of 2019 and then spread worldwide, particularly to Italy, Spain, USA, and Iran. Currently, Coronavirus Disease 2019 (COVID-19) is a main public health issue. As of April 9, 2020, more than a million confirmed cases of COVID-19 with more than 90,000 deaths have been reported in 202 countries by WHO. The 2019-nCoV can be spread by direct contact or droplets between humans and shows great potential for a pandemic. At present, there is no particular antiviral therapy for 2019-nCoV-infected persons, however, a wide range of therapeutic agents are being examined. The capabilities inherent to nanotechnology hold a large guarantee in presenting innovative approaches in the field of COVID-19 prevention, diagnosis, and cure.
Methods: Reviewing and evaluating the researches that have been done in the past and the materials that have been published.
Results: We in this article discuss how nanotechnology can improve the treatment of persons infected with COVID-19 virus.
Conclusion: As shown in this review, remarkable works have been done in nanoformulation therapeutics for treatment of the lung infections. Nanotechnology presents an excellent opportunity for the basic improvement of current treatments and development of novel therapeutic options for lung infections formerly thought impossible or difficult to treat. Nonetheless, we are yet in the primary stages of nanomedicine in respiratory infections care, which requires physicochemical and nanotoxicological analysis for possible human applications. At present, we are entering a modern world where nanotherapeutics will change the way we practice respiratory medicine. Nanotherapeutics offer improved clinical efficacy for patients, especially to those patients who are currently treatment-resistant to conventionally administered therapeutics.
According to the above content and the potential applications of nanotechnology to delivery of anti-infection drugs to the lungs, current and potential therapeutics of COVID-19 can be encapsulated into nanocarriers and delivered to the lungs through the respiratory tract.