- Review and comparison of treatment and effectiveness of some methods of treating brain cancer
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Razieh Eini,1,*
- Introduction: Introduction:
Meningioma and glioma are the most common and malignant cancers of the brain, respectively. Proton therapy in meningioma and glioma shows significant thematic control and it has low side effects and thus has an example on the patient's quality of life. Clinical data are limited in carbon therapies (CIRT) however, the available information confirms the reduction of toxicity and side effects of this method and the high degree of local control of this method. Proton therapy and carbon therapy are used continuously in the treatment of glioma, and in this disease, it is more possible to use high-dose radiation. However, many studies are needed for the therapeutic effects of both methods and the effect on cognitive approaches and neural functions. Hyperbaric oxygen therapy (HBO) is also used as an adjunct therapy for some brain cancers and is done as a way to overcome tissue oxygen depletion. Hypoxia is one of the causes of ineffectiveness of clinical treatments. HBO can be effective in treating malignant gliomas, and combining this method with radiotherapy can be more effective than radiotherapy alone, as well as reducing the side effects of cytotoxic chemotherapy drugs.
- Methods: Method:
In this study articles related to brain cancer in recent years was searched from the pubmed database. The clinical results of various studies and treatments for two common types of brain cancer, including meningioma and glioma, were evaluated.
- Results: Result:
According to the general results of research, some adjunctive therapies, including radiotherapy, may cause complications such as thromboembolism due to the sensitivity of the cerebral arteries. The results of chemotherapy research studies show that some chemotherapy drugs may cause micrometastasis in the brain. and in general, chemotherapy drugs in brain cancer create a brain environment for the growth of brain tumors.
- Conclusion: Conclution:
In general, traditional methods of treating cancer, including radiotherapy and chemotherapy, can not be successful in treating brain cancer. Treatment of various types of brain cancers requires further research and new therapies. Some results of nanoscience treatment have shown significant effectiveness. Nanodrugs and nanoparticles have shown significant results in treatment due to the sensitivity of Cerebral vessels and blood brain barrier. And these treatments seem to have acceptable results in combination with other methods such as proton therapy and carbon therapy and other methods.
- Keywords: meningioma, glioma, hypertensive oxygen therapy, adjunctive therapie