1. Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
Introduction
Metabolic syndrome, a coexisting of high blood glucose, obesity, dyslipidemia and
hypertension, is an important risk factor for cardiovascular disease occurrence and mortality.
recently, there is a rising demand for herbal drugs which have less adverse effects and have shown
more beneficial effects in comparison with synthetic options. red pepper, with the scientific name of
capsicum annuum
, belongs to the solanaceae family. the lipid-lowering, antihypertensive, antidiabetic
and anti-obesity effects of
c. annuum
have been demonstrated in several studies.
Methods
in this review, we summarized different animal and human studies on the
effect of red pepper and capsaicin on different components of metabolic syndrome which are risk
factors for cardiovascular diseases (cvds).
Results
according to these studies, red pepper as well as capsaicin has ability to control of
metabolic syndrome and its related disorders such as obesity, disrupted lipid profile, diabetes and its
complications.
Conclusion
red pepper has beneficial effects on metabolic syndrome and can decrease the risk of
mortality due to cardiovascular diseases, but still more research projects need to be done and confirm
its advantageous especially in humans.
